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Hearing test East Devon

Hearing test East Devon

Hearing test East Devon at the Honiton Hearing Centre.

 

Hearing test East Devon at the Honiton Hearing Centre. We all need good hearing and that’s just a fact. Imagine not being able to hear the door bell, or hear your new grand child as they talk to you wanting to find out about Gran or Grandad. There are so many ways we need hearing in our daily life. Just talking to someone without lip reading your way through the conversation hoping to catch what they are saying so you can respond correctly. It can be stressful not being included in what is going on around you.

To watch how we conduct hearing tests click here 

Honiton hearing can help, we are specialist hearing care practitioners with many years in the hear care business.  Colin Eaton is a specialist in ear wax removal and dispensing hearing aids after the comprehensive hearing test known to man kind in Devon. If your ears are clear of wax and after the hearing test Colin will sit with you and explain carefully what he has found regards your hearing. He will show you on a screen the test results so you are in complete control of your next move.

With knowledge of the hearing results Colin will then guide you on what hearing aid or aids are best suited to your hearing needs. It maybe after the hearing test you don’t actually need hearing aids. Knowledge is a good thing either way.  Just like eye examinations, hearing tests are just as much needed when you reach a certain age. If you think you may benefit from a hearing test then please book an appointment with Sam on reception or use the booking form here to make a booking.

 

To book your free hearing test click here 

 

 

 

New hearing aids Devon

New hearing aids Devon

 

New hearing aids available in Devon by Honiton hearing

 

New hearing aids available Devon at the Honiton hearing centre. A new style of hearing aid is now available for the younger generation. Made by Oticon. OPN Play. These hearing aids are available at specialist children’s centres who cater for children hearing loss. Many people suffer from hearing loss and we at the Honiton hearing centre do cater for the older generation. We also conduct hearing tests and remove ear wax by appointment. Digital hearing tests are available again by appointment. The new Oticon Opn Play are designed for children only, but we have the adult Opn selection in our Honiton store.

Ear wax removal Devon

Once we conduct a full spectrum hearing test we will go through the results with you to determine what hearing loss you may have and if any what type of remedy we can offer. This maybe through hearing aids or ear wax removal.

Please click here to watch our video on how we remove ear wax using Microsuction.

Hearing aids available Devon

 

Honiton Hearing News:

Oticon Introduces Opn Play

Oticon Opn Play

Honiton hearing centre

Oticon announces Opn Play™, a new child-friendly hearing solution, is said to “improve speech understanding in simple and complex listening environments and provides access to multiple speakers, without reducing environmental sounds important to incidental learning and safety.” The new Velox S™platform fuels Opn Play to provide children with the best possible conditions to grow, thrive, live, and learn, according to the company.

Tiverton ear wax removal

According to pediatric best practice guidelines, it is crucial to give children as much of the auditory environment as possible, in particular speech, to create the best opportunities for learning and language development.* Opn Play featuring OpenSound Navigator™ (OSN) helps accommodate best practice by delivering the “optimal signal-to-noise ratio across varying listening environments to constantly optimize learning opportunities.” Unlike traditional omnidirectional and directional approaches, OSN reportedly gives children the best of both worlds—“always open” access to a balanced soundscape that helps support the natural way the brain makes sense of sound, even in difficult listening environments.

A study at Boys Town National Research Hospital with children ages 6-15 reported that OSN offered an average of 4 dB SNR improvement in speech recognition (up to 30%) whether the child faced the speaker directly or faced away. The same study found that OSN preserves competing speech to allow access to multiple talkers, supporting incidental learning for children.

“Young children naturally learn a tremendous amount from overhearing or incidental listening, but children with hearing loss have fewer opportunities to learn by overhearing, especially when they are not looking directly at the talker,” said Maureen Doty Tomasula, AuD, senior product & marketing manager, Oticon Pediatrics. “The ability of OpenSound Navigator to preserve speech coming from different locations allows access to other talkers in the background, which is fundamental to incidental learning in school-age children.”

In a separate study of listening effort for children, researchers at VU University Medical Center in Amsterdam found that OSN improves speech understanding by up to 5 dB SNR with less perceived effort compared to traditional omnidirectional technology.**

Devon ear syringing

Powered by the new Velox S platform, Opn Play reportedly analyzes sound at 56,000 times/second to give children access to speech details with “more natural sound and increased comfort,” according to Oticon.  OpenSound Optimizer™, a new technology in Opn Play, uses “ultra-fast” detectors and a patented breaker signal to proactively manage feedback, even before it occurs. Hearing care professionals can now fit children with up to 6 dB more gain, helping to allow more stable gain for closed fittings and more open fittings. This helps enable Opn Play to provide the brain with up to 25% more speech cues, without the risk of feedback.***  The new technology helps ensure stable access to speech details to support better language development and is said to allow children to play, hug, interact, and wear hats and helmets without feedback.

Easy Connectivity at School and Home

Opn Play offers compatibility with existing classroom solutions. A new option—Opn Play plus Oticon ConnectClip—can enhance incidental listening and communication between parents and children with hearing loss, especially when there is distance or noise present, such as when riding in the car, at the playground, or in a stroller. ConnectClip helps make it easy for children to stay connected to the most important speakers in their lives, parents, friends, teachers, and coaches. Opn Play is Made for iPhone® and connects with smartphones, laptops and other Bluetooth®-enabled devices. 

Lyme Bay Devon, ear syringing

The Opn Play miniRITE R offers a rechargeable lithium-ion solution in a “discreet design,” helping to eliminate the hassle of handling and replacing batteries every few days. The charger features a stable magnetic connection and is said to deliver a full day of power, including streaming, with an overnight charge.

Oticon_Opn_play_4_Colours_product_lineup_cutout

        Hearing aids Bristol

The Oticon Opn Play family is available in fitting ranges from mild to severe across all styles and in an array of kid-friendly colors. For more information about the entire Oticon Opn Play family, visit: www.oticon.com/opn-play.

* American Academy of Audiology (AAA) Clinical Practice Guidelines Pediatric Amplification June 2013
** Ng E, Goverts T, et al. (2019). Oticon Whitepaper.

*** Speech Intelligibility Index. ANSI S3.5.

Source: Oticon

Image: Oticon 

Depression and Hearing link

Depression and Hearing link

 

Depression and Hearing link, Devon. The Honiton hearing centre are well aware of the link between loss of hearing and depression.

Depression and Hearing link, Devon. Colin Eaton, audiologist, who is based at the Honiton hearing centre knows that Depression and hearing can be linked.

Depression and hearing link found by researchers.

New report into depression and hearing has been published. We at the Honiton hearing centre are well aware of this link and can help with making your hearing a little better.

Exeter hearing and Ear wax removal centre

 

Devon hearing and Ear wax removal centre is at the Honiton hearing centre the independent hearing and ear wax specialist covering Exeter, Tiverton, & Sidmouth.  If you are having issues with hearing in general we can conduct a hearing test at Honiton. The comprehensive hearing test will take around an hour of your time, but the results will be know there and then putting you in control of your hearing. We can then discuss what hearing instrument (hearing aid) you may need if required.  There could be other issues at play if you are not hearing as well as you think you should be. We can before the test look to see if you have any ear wax present. Ear wax isn’t usually an issue, we all need a little for good ear health. However in some cases excessive ear wax build up can become an issue and if you have excessive ear wax we will clear this before any test is conducted.

Depression and Hearing link, Devon

Ear wax removal is very easy and painless. We use the Micro-suction ear wax removal method as this really is the gold standard of ear wax removal. We also can use the older method of ear wax removal called irrigation or some may know this as ear syringing. This method uses warm water to gently irrigate the ear to help release the ear wax out from the ear.

You can learn about our ear wax removal here

 

So if you are having some hearing issues and would like a family run professional ear wax removal service then book an appointment. We can discuss at the appointment any of the issues at length. After all we are all ears!

 

Ear wax removal Devon

 

Honiton hearing News:

Bringing world wide news on hearing to our local area.

 

Study Shows Older Adults with Hearing Loss at Higher Risk for Depression

 

Hearing loss is linked to depression

Honiton hearing centre

The results of a study investigating the connection between hearing loss and depression found that older adults with some form of hearing loss were 47% more likely to also have depression symptoms, according to an article in Reuters

Lyme bay Hearing centre

Originally published in The Gerontologist, the research reviewlooked at 35 previous studies encompassing 147, 148 participants, who were at least 60 years old.

“We know that older adults with hearing loss often withdraw from social occasions, like family events because they have trouble understanding others in noisy situations, which can lead to emotional and social loneliness,” lead study author Blake Lawrence of the Ear Science Institute Australia, in Subiaco, and the University of Western Australia in Crawley, was quoted as saying in Reuters. 

Additionally, the article goes on to add that the brain may work harder to interpret sound from a weaker auditory signal, draining resources needed to maintain working memory or other cognitive functions. A weaker signal may also cause the “reorganization” of neural pathways, potentially changing the way depression is regulated in the brain.

Ear syringing East Devon

In a new white paper produced by The Hearing Review and sponsored by Hamilton CapTel, “Depression, Hearing Loss, and Treatment with Hearing Aids,” audiologist and educator Victor Bray, PhD, reviews previous landmark studies as well as more recent research into the complex relationship between hearing loss and depression. The paper helps identify patient populations who might benefit most from hearing devices. Additionally, Dr Bray’s webinar “Depression, Hearing Loss, and Treatment with Hearing Aids,” discusses the risk factors for depression among people with hearing loss as well as why hearing care providers should screen for depression when risk factors are present.

Original Paper: Lawrence BJ, Jayakody DMP, Bennett RJ, Eikelboom RH, Gasson N, Friedland PL. Hearing loss and depression in older adults: a systematic review and meta-analysisThe Gerontologist. 2019:1-19. DOI: https://doi.org/10.1093/geront/gnz009

Source: Reuters, The Hearing Review, The Gerontologist

Ear wax removal near Tiverton Devon

Ear wax removal near Tiverton Devon

 

Ear wax removal near Tiverton Devon is available at the Honiton hearing centre. If you are suffering from excessive wax build up in the ear or ears we can come to your aid. Using Microsuction or the traditional irrigation technique, (some call it ear syringing), it only take a few mins to painlessly  remove excess ear wax. Please click here to see how Micro-Suction works via our new online video.

To see how ear syringing works please click here. 

If you live in Tiverton area then contact us for Ear wax removal near Tiverton Devon

Honiton hearing centre also conduct lots of other ear related issues such as hearing tests, dispensing the very latest digital hearing aids along with hearing aid servicing and setting up of new hearing aids after you purchase them. If you need any of our services please book in using our online booking calendar or call Sam on reception.

 

Honiton hearing news:

Philips Hearing Aids Introduced by Demant

Published on 

Philips-Hearing-Aids-Honiton-Hearing-Devon

Honiton hearing Devon

Demant, Copenhagen, Denmark, has announced the introduction of Philips branded hearing aids to the global hearing aid market, according to a press release from the company. A new player, the Philips brand is entering the hearing healthcare market with a complete range of premium hearing aids, accessories, and applications to best serve hearing aid users. Demant states Philips Hearing Solutions will quickly become a trusted brand with hearing care providers and users, as it has great potential around the world to present unique opportunities for hearing care professionals in an ever-evolving market.

In August, Demant  announced a licensing agreement with Philips, which is headquartered in Eindhoven, The Netherlands, to bring Philips-branded solutions to the hearing healthcare market.  Demant (formerly William Demant Holding) is the parent group of Oticon, Sonic, and Bernafon hearing aids, as well as Oticon Medical.

Ear wax removal near Tiverton Devon

“Based on a shared vision of improving the lives of people through innovative healthcare this new cooperation will not only change the way we see hearing healthcare, but also widen the definition of hearing healthcare, supporting healthier lifestyles and active aging,” said Spencer Ramsey, Senior Director of Brand Licensing, Philips, in the press statement. “Combining Demant’s world-leading hearing aid technology with Philips’ global brand presence in healthcare, the cooperation will enrich the hearing healthcare experience.”

The new premium Philips hearing aids—named Philips HearLink—are now available for hearing care professionals in selected countries. The look and feel of the Philips HearLink hearing aids is designed to cater to today’s baby boomer generation with design and usability developed for this expanding market. Philips HearLink users will benefit from connectivity between their hearing aids and the devices they use in their everyday life, such as smartphones and televisions. The hearing aids will reportedly be manufactured by Demant using the Velox-S and Velox platforms, and will be available in a complete range of styles, including RICs, BTEs, ITCs, CICs, and IITs.

Demant President Søren Nielsen provided an overview of the Oticon Opn S and Opn Play at an investor and media presentation.

Søren Nielsen

“The Philips hearing aids will provide users with an innovative, future-proof hearing solution,” says Demant President & CEO Søren Nielsen. “We live in an age where user engagement and digital services are shaping the future of healthcare technology. More and more people are conscious of taking control of their own personal healthcare and are using electronic devices to do so. In this light, Philips Hearing Solutions offers new and exciting premium solutions alongside Philips’ healthcare ecosytem, which will attract interest and generate significant benefits to users, ultimately supporting our valued customer base of hearing care professionals.

Tiverton ear wax removal at the Honiton Hearing centre

“With this partnership, we take connected hearing healthcare to the next level and offer new and exciting solutions within integrated healthcare services to the benefit of both professionals and people suffering from a hearing loss,” continued Nielsen. “Health, caring, and innovation are cornerstones in the vision of both Demant and Philips, which makes the partnership a great match for the future. Furthermore, it will strengthen and add value to both companies’ ambition to improve people’s lives.”

The Philips brand is something of a “back to the future moment” for more seasoned dispensing professionals. Philips was a well-known hearing aid brand in the 1990s, and the company embarked on a technical collaboration with Telex then exited the market just before the turn of the new century when Beltone purchased Philips’ hearing aid technology. The Hearing Review published numerous news and technical articles about Philips technology in the 90s.

Traditionally, hearing aid branding has not played a large role in hearing healthcare; MarkeTrak 9 suggested that less than half of hearing aid users (43%) could identify the brand of their device. However, many experts in the industry believe this is due to change, as more consumers are expected to enter the market and there is continued competition and aggressive marketing among dispensing chains, pharmacies, mass merchandisers, and online retailers. The Philips brand brings with it one of the world’s best known and trusted healthcare and consumer electronics brands.

For further information about Philips Hearing Solutions and a full presentation of the Philips HearLink product range, visit: hearingsolutions.philips.com

New hearing aids Devon

New hearing aids Devon

 

New hearing aids in Devon at the Honiton hearing centre. We are used to new hearing aids arriving from various manufacturers all year round, but when something is really new and exciting we love to tell you and our existing clients why we are so excited.

Hearing aids have evolved in recent years. Digital hearing aids have made the devices so small and powerful they are no longer what people expect to see. The huge hearing aid of old is getting less visible these days, the new as powerful hearing aids are now tiny. If you are looking for new hearing aids in Devon, we are the place for you!

New hearing aids Devon

The tech inside these little wonders are amazing on so many levels. Take one of the many things they can do. They can connect to your mobile phone and you can talk wirelessly without the phone in your hand as if you were talking to a person next to you. The hearing aid is catching your voice and transmitting this to your phone via bluetooth. You can hear perfectly as your hearing aid is in your ear so you don’t have to really listen hard to get what the conversation is. It’s all done without you doing anything. This tech isn’t new, it has been around for some years, but if your hearing aids are not ”Connected” versions, then maybe when you are next due a new set of hearing aids, you can ask to be told of what’s new in this ”Connected” world.

Devon hearing aid centre

Colin Eaton the lead audiologist at Honiton hearing will be happy to show you and explain all about what is new and on offer. He will also show you how you connect your new digital hearing aid with various tech such as mobile phones, ipads, and the T.V.

make your appointment with Colin now by calling Sam on reception or use the booking form here.

Honiton hearing news:

 

Semtech and Sonova Launch Jointly-Developed Radio System

Digital hearing aids, Devon

Latest Digital hearing aids at the Honiton hearing centre, Devon

Semtech Corporation (Nasdaq: SMTC), a supplier of high-performance analog and mixed-signal semiconductors and advanced algorithms, and Sonova, a developer of hearing care solutions, announced a jointly developed advanced radio system. The ultra-small integrated circuit (IC) is said to be a main component for a new generation of hearing aids, enabling support for multiple radio protocols in the 2.4GHz band, as well as effective operation on very low power, according to the announcement.

New hearing aids Devon

“This chip allows Sonova to move in a new direction with our hearing aids,” said Marc Secall, director, research & development, wireless, at Sonova. “The breakthrough radio technology and power management are the game changers for hearing aids. It allows them to support a number of applications that have previously not been possible in a hearing aid, all at low power consumption and low supply voltage. Possible applications span from connectivity to any Bluetooth®-enabled audio device (eg, a smartphone or television) to full duplex audio streaming between hearing aids and connectivity to wireless microphones.”

Ear wax removal Devon

“Semtech continues to innovate and create flexible, reliable solutions for challenging applications associated with the best radio frequency connectivity at the lowest power and 0.8V supply voltage,” said Jean-Paul Bardyn, vice president of research and development of Semtech’s wireless and sensing products group. “Sonova has long been a leader for hearing devices. By implementing Semtech’s technology and enabling access to the Cloud, we believe that these devices will enrich the IoT-connected solutions which Semtech is serving with LoRa Technology.”

Source: Semtech, Sonova

Images: Semtech, Sononva

New video on hearing aid batteries

New video on hearing aid batteries

 

We have shot a new video on how hearing aid batteries need to be looked after and the differences in them. Little nuggets of info that you may, or may not know, on how to get the most of your hearing aid batteries. If you need hearing aid batteries in the Honiton area then pop in and buy what you need, or if you need help in any way we will be glad to show you.

Click here to see the new hearing aid battery video 

 

Hearing aid batteries, hearing test, ear wax removal, Devon, South Devon

Hearing aid batteries available at the Honiton hearing centre

Honiton hearing centre for all 2019 hearing aids

Honiton hearing centre, for the very latest digital hearing aids.

Looking for information on how what hearing aids would suit you or what you need? Book an appointment with the Honiton hearing centre and have a full spectrum hearing test done. Once the test has completed Colin Eaton will sit with you and discuss the results. Once they results are know he will then go through what the different types of hearing aids (if any needed) are good for your hearing loss. There are many hearing aids available form many different manufacturers. The Honiton hearing centre are an independent hearing centre, covering the whole of Devon and Somerset. We are not affiliated to any manufacturer so can offer you what you need rather to what we sell. We can access all the major manufactures hearing aids for you to choose from.

Click here to watch what type of  hearing aids do you need?

Honiton Hearing News:

New Hear-it Report Documents Extraordinary Costs of Hearing Loss in EU

Published on February 27, 2019

hear-it_tw_400x400

In the EU, untreated hearing loss costs 185 billion Euro–each year. –hear-it.org

A new scientific report, “Hearing Loss – Numbers and Costs”, concludes that untreated, disabling hearing loss costs 185 billion Euros (US$211 billion) in the EU each year. This represents 8,200 Euros  (US$9335) each year per person with an untreated disabling hearing loss.

The detailed findings and conclusions in the report will be presented at a lunch debate at the European Parliament in Brussels, Belgium, on the March 6 in connection with the WHO World Hearing Day on the 3rd of March.

The report was carried out for the non-profit organization, hear-it AISBL, by Professor Emerita Bridget Shield with the assistance of Professor Mark Atherton at Brunel University in London. In 2006, Professor Bridget Shield compiled the first report for hear-it AISBL, “Evaluation of the Social and Economic Costs of hearing Impairment.”

How they arrived at the 185 billion Euro figure. According to the report, lower quality of life due to disabling hearing loss costs the EU 130 billion Euros (US$148 billion) each year. Lost productivity in society due to a higher unemployment among people with a disabling hearing loss costs 55 billion Euros ($63 billion) each year in the EU. In total, this is 185 billion Euros. The cost does not cover extra health care costs caused by hearing loss. A disabling hearing loss is defined by the Global Burden of Disease research group (GBD) as a hearing loss of 35 dB or greater.

In Europe as a whole—including non-EU countries—untreated, disabling hearing loss costs 216 billion Euros (US$246 billion) each year, says the researchers.

Honiton hearing centre for all 2019 hearing aids

The report documents that the use of hearing aids and other hearing solutions improves health and increases quality of life. It also documents that people with an untreated, disabling hearing loss are at greater risk of social isolation, depression, cognitive decline and dementia, while people who treat their hearing loss do not experience a higher risk than people without hearing loss.

There are 34.4 million people with a disabling hearing loss (35 dB or greater) in the EU. More than 22.6 million are not treated for their disabling hearing loss as only around 1 in 3 in Europe with a disabling hearing loss use hearing aids or other hearing solutions. This is more than the combined population of Austria, Finland, Ireland, and Lithuania. With a steadily aging population who live longer and with an earlier onset of hearing loss due to increased noise exposure, this growth will increase even further in the years to come, warns Hear-it.

Honiton hearing centre for all 2019 hearing aids

A meta study. The report, “Hearing Loss–Numbers and Costs”, is a meta study which has analyzed and compared hundreds of scientific studies and papers in the last two decades about the prevalence and the consequences of hearing loss and the use and benefits of hearing aids, according to the organization.

Kim Ruberg

Kim Ruberg

“The scientific report clearly demonstrates that untreated hearing loss is a major health issue and that untreated hearing loss has a huge economic and social impact on our society,” said Secretary General Kim Ruberg, hear-it AISBL, on the organization’s website. “It also documents that checking your hearing and treating hearing loss pays, both for the individual and for society.”

Check your hearing. World Hearing Day is held by the WHO on the 3rd of March each year to raise awareness of how to prevent deafness and hearing loss and promote ear and hearing care across the world. The theme for World Hearing Day 2019 is “Check your hearing”.

Honiton hearing centre for all 2019 hearing aids

“If you think you might have a hearing loss, my best advice is to get your hearing checked,” says Ruberg. “You can start by checking your hearing using the WHO “Check your hearing” app, or test your hearing online at www.hear-it.org. But if you suspect that you have hearing problems my best advice is that you get a real hearing test carried out by a hearing professional,” says Ruberg.

Source: Hear-it

Honiton hearing centre, Devon

Honiton hearing centre, Devon

 

 

Honiton hearing centre caters for all types of hearing loss and ear wax removal. Colin Eaton, the lead audiologist at the Keynsham hearing centre has over 15 years audiology expertise to make sure his clients get the best hearing result no matter what the hearing issues are.

Ear wax removal is available by appointment and a limited amount of out of hours appointments are available but please call Sam on reception if you require out of hours.

Comprehensive hearing tests are also available. Please make sure that any ear wax issues are clear before you take the test, if you need ear wax removing prior the test please call reception and make this clear to Sam that you will need ear wax clearing first.

If you are confused on what hearing aids are for and for what type of hearing loss, please watch our new video here that explains why so many different types of hearing aids there are.

 

Honiton hearing centre, News

Researchers Restore Hearing via Gene Therapy in Deaf Mouse Model

Published on 

In collaboration with the universities of MiamiColumbia, and San Francisco, scientists from the Institut Pasteur, InsermCNRSCollège de FranceSorbonne University, and the University of Clermont Auvergne have managed to restore hearing in an adult mouse model of DFNB9 deafness, a hearing disorder that represents one of the most frequent cases of congenital genetic deafness, Institut Pasteur announced on its website. Individuals with DFNB9 deafness are profoundly deaf as they are deficient in the gene coding for otoferlin, a protein which is essential for transmitting sound information at the auditory sensory cell synapses. By carrying out an intracochlear injection of this gene in an adult DFNB9 mouse model, the scientists successfully restored auditory synapse function and hearing thresholds to a near-normal level. These findings, published in the journal PNAS, open up new avenues for future gene therapy trials in patients with DFNB9.

Honiton hearing centre Devon

The left panel is a schematic representation of the human ear. Sound waves are collected by the outer ear made up of the pinna and ear canal. The middle ear, composed of the eardrum and ossicles, transmits sound waves to the inner ear, which features the cochlea – the hearing organ responsible for transmitting auditory messages to the central nervous system. The right panel shows an immunofluorescence image of the auditory sensory epithelium within an injected cochlea. The inner hair cells have been stained for otoferlin in green. Otoferlin is detected in almost all of these cells. The inset is a high magnification area showing an inner hair cell that has not been transduced. © Institut Pasteur

The left panel is a schematic representation of the human ear. Sound waves are collected by the outer ear made up of the pinna and ear canal. The middle ear, composed of the eardrum and ossicles, transmits sound waves to the inner ear, which features the cochlea – the hearing organ responsible for transmitting auditory messages to the central nervous system. The right panel shows an immunofluorescence image of the auditory sensory epithelium within an injected cochlea. The inner hair cells have been stained for otoferlin in green. Otoferlin is detected in almost all of these cells. The inset is a high magnification area showing an inner hair cell that has not been transduced. © Institut Pasteur

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Over half of nonsyndromic profound congenital deafness cases have a genetic cause, and most (~80%) of these cases are due to autosomal recessive forms of deafness (DFNB). Cochlear implants are currently the only option for recovering hearing in these patients.

Adeno-associated viruses (AAVs) are among the most promising vectors for therapeutic gene transfer to treat human diseases. AAV-based gene therapy is a promising therapeutic option for treating deafness but its application is limited by a potentially narrow therapeutic window. In humans, inner ear development is completed in utero and hearing becomes possible at approximately 20 weeks of gestation. In addition, genetic forms of congenital deafness are generally diagnosed during the neonatal period. Gene therapy approaches in animal models must therefore take this into account, and gene therapy efficacy must be demonstrated following a gene injection when the auditory system is already in place. In other words, therapy must reverse existing deafness. The team led by Saaïd Safieddine, a CNRS researcher in the Genetics and Physiology of Hearing Unit (Institut Pasteur/ Inserm) and coordinator of the project, used a mouse model of DFNB9, a form of human deafness that represents 2-8% of all cases of congenital genetic deafness.

Ear wax removal South Devon

DFNB9 deafness is caused by mutations in the gene coding for otoferlin, a protein that plays a key role in transmitting sound information at the inner hair cell synapses. Mutant mice deficient in otoferlin are profoundly deaf as these synapses fail to release neurotransmitters in response to sound stimulation, despite the absence of detectable sensory epithelial defects. DFNB9 mice therefore constitute an appropriate model for testing the efficacy of viral gene therapy when it is administered at a late stage. However, as AAVs have limited DNA packaging capacity (approximately 4.7 kilobase (kb)), it is difficult to use this technique for genes whose coding region (cDNA) exceeds 5 kb, such as the gene coding for otoferlin, which has a 6 kb coding region. The scientists have overcome this limitation by adapting an AAV approach known as dual AAV strategy because it uses two different recombinant vectors, one containing the 5’-end and the other the 3’-end of the otoferlin cDNA.

A single intracochlear injection of the vector pair in adult mutant mice was used to reconstruct the otoferlin coding region by recombining 5′ and 3′-end DNA segments, leading to long-term restoration of otoferlin expression in the inner hair cells, and then restored hearing.

Honiton hearing centre, Devon

The scientists have therefore obtained initial proof of the concept of viral transfer of fragmented cDNA in the cochlea using two vectors, showing that this approach can be used to produce otoferlin and durably correct the profound deafness phenotype in mice.

The outcomes achieved by the scientists suggest that the therapeutic window for local gene transfer in patients with DFNB9 congenital deafness could be wider than thought, and offers hope of extending these findings to other forms of deafness. These results are the subject of a patent application filed.

Hearing aids Tiverton, Devon

In addition to the institutions mentioned in the first paragraph, this research was funded by the French Foundation for Medical Research, the European Union (TREAT RUSH), and the French National Research Agency (EargenCure and Lifesenses LabEx).

Original Paper: Akil O, Dyka F, Calvet C, et al. Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model. PNAS. 2019. DOI: https://doi.org/10.1073/pnas.1817537116

Source: Institut Pasteur, PNAS

Image: Institute Pasteur

Best ear wax removal, Honiton Devon

Best ear wax removal, Honiton Devon

 

The Best ear wax removal, Honiton Devon, is at the family owned and run independent Honiton hearing centre. Covering the whole of Devon including Tiverton, Exeter Lyme bay and Sidmouth.

The Honiton hearing centre based in Honiton and is the place to book for ear wax removal and hearing tests. If you are suffering from Tinnitus Colin Eaton the lead audiologist at the Honiton hearing centre can help you with Tinnitus therapy.  Local GP surgeries are no longer treating ear wax removal as part of the NHS but if you are in serious need and want to book an appointment please call Sam on reception to book your ear wax removal session. Please read the website for costs.

 

Watch our hearing test video here and our ear wax removal using Microsuction here.

 

Honiton Hearing News:

Best ear wax removal, Honiton Devon

 

Oticon Releases Survey Highlighting Tinnitus Prevalence in the UK

Original Story by The HEARING REVIEW

Oticon Logo

For a second year, the British Tinnitus Association is hoping to raise awareness of the prevalent condition suggested to severely affect 1 in 10 of the population. People with tinnitus have a hidden condition making it difficult for others to understand what they are going through. This year’s Tinnitus Week theme will draw attention to how many people feel isolated and unable to talk to their loved ones, friends, or colleagues about their condition.

A nationally representative hearing loss survey of 2,000 UK adults commissioned by hearing aid manufacturer Oticon, reveals just how prevalent tinnitus is and highlights the importance of recognition and education of the sometimes debilitating condition, the hearing aid manufacturer announced. An alarming 21% of respondents experience tinnitus symptoms such as ringing, buzzing, or persistent noise in the ears. Among these respondents, less than half have seen a doctor or hearing care professional about their symptoms, 25% do not think that they need to, and worryingly, almost 40% are not concerned about their overall hearing health, despite nearly half reporting that they do not have good hearing.

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To underline the significance of this year’s Tinnitus Week theme of isolation, the Oticon survey reveals that the biggest effect of the widespread hearing condition is withdrawal from social situations, which 28% reported. This is followed by lack of concentration (26.4%), less alertness (25.8%), and stress (22.4%). Furthermore, two thirds experiencing tinnitus symptoms find it tiring to hear what people are saying and follow conversations in situations where there are lots of people speaking.

Alison Stone, training manager and audiologist at Oticon, says: “People with tinnitus are often more tired and can have more difficulty concentrating, especially if there is background noise in the environment. They are also more at risk of high anxiety, depression, and irritation which affects their daily quality of life a great deal. Isolation is a natural response to many of the effects of tinnitus which is why the support of friends and family is so important. We urge those with tinnitus to talk, and although there is no known cure, to explore the management options available to relieve their symptoms which could significantly minimize the impact the condition has on their life. There are trained professionals out there who understand and can help.”

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The Oticon survey results highlight that tinnitus can be experienced by anyone, with between 16% and 24% of respondents reporting symptoms in each age category. Tinnitus can indeed be experienced by anyone, as well as be temporary or permanent, constant or intermittent.

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Oticon’s Alison Stone advises: “We know that approximately 80% of those with hearing loss also have tinnitus, and 80% of those with tinnitus also have some form of hearing loss. It’s important to highlight that tinnitus can sometimes be a symptom of a treatable medical condition, so, if you are experiencing any tinnitus symptoms seek professional medical advice from your primary care doctor or an ENT consultant. Early intervention could make a difference.”

Tinnitus Week aims to increase awareness of tinnitus with a week of promotions that highlight the impact tinnitus can have on the lives of the many people affected. For more information about the condition visit: https://www.oticon.global/hearing/what-is-hearing/tinnitus

Source: Oticon, British Tinnitus Association 

Hearing aids East Devon

Hearing aids East Devon

The Honiton hearing centre

 

Hearing aids East Devon, at the Honiton hearing centre run by Colin and Sam Eaton. Digital hearing aids have changed beyond recognition in the last 5 years. If you are using older hearing aids or have been using NHS hearing aids and would like to try the latest discreet digital hearing aids with connectivity with your mobile phone, tablet and T.V. Honiton hearing offer a free trial. Please contact Sam on reception. We use PhonakGN ReSoundOticon and other manufacturers hearing aids.

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The Honiton hearing centre also conduct ear wax removal using Microsuction and the traditional water irrigation technique. You can watch our video here to see how we do this and how painless and quick it really is.

Honiton hearing news:

Researchers Identify Gene Associated with Age-related Hearing Loss

 

Mouse study reveals contributor to hearing loss

An international group of researchers, led by Ronna Hertzano, MD, PhD, associate professor, Department of Otorhinolaryngology-Head & Neck Surgery, at the University of Maryland School of Medicine (UMSOM), and Michael Bowl, PhD, program leader track scientist, Mammalian Genetics Unit, MRC Harwell Institute, UK, have identified the gene that acts as a key regulator for special cells needed in hearing.

The discovery of this gene (Ikzf2) will help researchers better understand this unique type of cell that is needed for hearing and potentially develop treatments for common age-related hearing loss, UMSOM announced.

“Outer hair cells are the first inner ear cells lost as we age,” said Hertzano, whose research will be published in the journal Nature. “Age-related hearing loss happens to everyone. Even a 30-year-old has lost some of the outer hair cells that sense higher pitch sounds. Simple exposure to sound, especially loud ones, eventually causes damage to these cells.”

The inner ear has two kinds of sensory hair cells required for hearing. The inner hair cells convert sounds to neural signals that travel to the brain. This compares to outer hair cells, which function by amplifying and tuning sounds. Without outer hair cells, sound is severely muted and inner hair cells don’t signal the brain. Loss of outer hair cells is said to be the major cause of age-related loss of hearing.

About the Research

Hertzano’s group, in collaboration with Ran Elkon, PhD, senior lecturer, Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine in Tel Aviv, Israel, took a bioinformatics and functional genomics approach to discover a gene critical for the regulation of genes involved in outer hair cell development. Bowl’s group studied mice from the Harwell Aging Screen to identify mice with hearing loss. Bowl identified mice with an early-onset hearing loss caused by an outer hair cell deficit. When the two groups realized that they were studying the same gene, they began to collaborate to discover its biological function and role in outer hair cell development. The gene is Ikzf2 gene, which encodes helios. Helios is a transcription factor, a protein that controls the expression of other genes. The mutation in the mice changes one amino acid in a critical part of the protein, which impaired the transcriptional regulatory activity of helios in the mice.

To test if helios could drive the differentiation of outer hair cells, the researchers introduced a virus engineered to overexpress helios into the inner ear hair cells of newborn mice. As a result, some of the mature inner hair cells became more like outer hair cells. In particular, the inner hair cells with an excess of helios started making the protein prestin and exhibited electromotility, a property limited to outer hair cells. Thus, helios can drive inner hair cells to adopt critical outer hair cell characteristics.

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Funding for the research was provided by Action on Hearing Loss UK, the National Institute on Deafness and Other Communication Disorders (NIDCD) at the National Institutes of Health, and the Department of Defense (DOD).

As Professor Steve Brown, PhD, director, MRC Harwell Institute, said, “The development of therapies for age-related hearing loss represents one of the big challenges facing medicine and biomedical science. Understanding the genetic programs that are responsible for the development and maturation of sound-transducing hair cells within the inner ear will be critical to exploring avenues for the regeneration of these cells that are lost in abundance during age-related hearing loss. The teams from the University of Maryland and the MRC Harwell Research Institute have given us the first insights into that program. They have identified a master regulator, Ikzf2/helios, that controls the program for maturation of outer hair cells. Now, we have a target that we can potentially use to induce the production of outer hair cells within damaged inner ears, and we are one step closer to offering treatments for this disabling condition.”

Original Paper: Chessum L, Matern MS, Kelly MC, et al. Helios is a key transcriptional regulator of outer hair cell maturation. Nature. November 21, 2018.

Source: University of Maryland School of Medicine, Nature

Image: University of Maryland School of Medicine